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E-AB-60480

LIG1 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-60480
Additional Names:
LIG1
Application:
IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human LIG1 (NP_000225.1).
Uniprot:
P18858
Synonyms:
DNA ligase 1;DNA ligase I;ligase I, DNA, ATP-dependent;polydeoxyribonucleotide synthase [ATP] 1
Extra Details:
This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice