E-AB-60463
THPO Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-60463
- Additional Names:
- MGDF,MKCSF,ML,MPLLG,THCYT1,THPO,TPO
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human THPO (NP_001171068.1).
- Uniprot:
- P40225
- Synonyms:
- c-mpl ligand;megakaryocyte colony-stimulating factor;megakaryocyte growth and development factor;megakaryocyte stimulating factor;MGDF;MKCSF;ML;MPL ligand;MPLLG;myeloproliferative leukemia virus oncogene ligand;prepro-thrombopoietin;THCYT1;thrombopoietin;TPO
- Extra Details:
- Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.
- Shipping Conditions:
- Blue Ice