E-AB-60437
AIRE Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-60437
- Additional Names:
- AIRE,AIRE1,APECED,APS1,APSI,PGA1
- Application:
- IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human AIRE (NP_000374.1).
- Uniprot:
- O43918
- Synonyms:
- AIRE1;APECED;APS1;APSI;autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein;autoimmune regulator;PGA1
- Extra Details:
- This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).
- Shipping Conditions:
- Blue Ice