E-AB-60287
MITF Polyclonal Antibody
Size
£211.50
Was £235.00
- SKU:
- E-AB-60287
- Additional Names:
- CMM8,COMMAD,MI,MITF,WS2,WS2A,bHLHe32
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human MITF (NP_937801.1).
- Uniprot:
- O75030
- Synonyms:
- bHLHe32;class E basic helix-loop-helix protein 32;CMM8;COMMAD;melanogenesis associated transcription factor;MI;microphtalmia-associated transcription factor;microphthalmia-associated transcription factor;MITF-A;WS2;WS2A
- Extra Details:
- This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
- Shipping Conditions:
- Blue Ice