E-AB-60286
TYR Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-60286
- Additional Names:
- ATN,CMM8,OCA1,OCA1A,OCAIA,SHEP3,TYR
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human TYR
- Uniprot:
- P14679
- Synonyms:
- ATN;CMM8;LB24-AB;monophenol monooxygenase;OCA1;OCA1A;OCAIA;oculocutaneous albinism IA;SHEP3;SK29-AB;tumor rejection antigen AB;tyrosinase
- Extra Details:
- The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
- Shipping Conditions:
- Blue Ice