E-AB-60245
HGF Polyclonal Antibody
Size
£211.50
Was £235.00
- SKU:
- E-AB-60245
- Additional Names:
- DFNB39,F-TCF,HGF,HGFB,HPTA,SF
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human HGF (NP_001010933.1).
- Uniprot:
- P14210
- Synonyms:
- DFNB39;F-TCF;fibroblast-derived tumor cytotoxic factor;hepatocyte growth factor;hepatocyte growth factor (hepapoietin A; scatter factor);hepatopoietin-A;HGFB;HPTA;lung fibroblast-derived mitogen;Scatter factor;SF
- Extra Details:
- This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss.
- Shipping Conditions:
- Blue Ice