E-AB-60230
CDC25A Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-60230
- Additional Names:
- CDC25A,CDC25A2
- Application:
- IHC, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human CDC25A (NP_963861.1).
- Uniprot:
- P30304
- Synonyms:
- CDC25 homolog A;CDC25A2;dual specificity phosphatase CDC25A;M-phase inducer phosphatase 1
- Extra Details:
- CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice