E-AB-60199
AMACR Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-60199
- Additional Names:
- AMACR,AMACRD,CBAS4,P504S,RACE,RM
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human AMACR (NP_976316.1).
- Uniprot:
- Q9UHK6
- Synonyms:
- 2-methylacyl-CoA racemase;alpha-methylacyl-CoA racemase;AMACRD;CBAS4;P504S;RACE;RM
- Extra Details:
- This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
- Shipping Conditions:
- Blue Ice