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E-AB-60133

PPIA Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-60133
Additional Names:
CYPA,CYPH,HEL-S-69p,PPIA
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human PPIA (NP_066953.1).
Uniprot:
P62937
Synonyms:
Cyclophilin A;cyclosporin A-binding protein;CYPA;CYPH;epididymis secretory sperm binding protein Li 69p;HEL-S-69p;peptidyl-prolyl cis-trans isomerase A;peptidylprolyl isomerase A (cyclophilin A);PPIase A;rotamase A;T cell cyclophilin
Extra Details:
This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported.
Shipping Conditions:
Blue Ice