E-AB-60015
BMI1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-60015
- Additional Names:
- BMI1,Bmi1,FLVI2/BMI1,PCGF4,RNF51,flvi-2/bmi-1
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human BMI1 (NP_005171.4).
- Uniprot:
- P35226
- Synonyms:
- B lymphoma Mo-MLV insertion region 1 homolog;BMI1;BMI1 polycomb ring finger oncogene;BMI1 polycomb ring finger proto-oncogene;COMMD3-BMI1 read-through protein;flvi-2/bmi-1;FLVI2/BMI1;murine leukemia viral (bmi-1) oncogene homolog;PCGF4;polycomb complex protein BMI-1;polycomb group protein Bmi1;polycomb group RING finger protein 4;ring finger protein 51;RNF51
- Extra Details:
- This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene.
- Shipping Conditions:
- Blue Ice