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E-AB-60014

BID Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-60014
Additional Names:
BID,FP497
Application:
IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human BID (NP_001187.1).
Uniprot:
P55957
Synonyms:
apoptic death agonist;BH3-interacting domain death agonist;desmocollin type 4;FP497;Human BID coding sequence;p22 BID
Extra Details:
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Shipping Conditions:
Blue Ice