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E-AB-53590

BACE2 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-53590
Additional Names:
ALP 56,ALP56,ASP1,ASP21,Asp 1,Aspartic Like Protease 56kDa,Aspartic-like protease 56 kDa,Aspartyl protease 1,BACE 2,BACE2,Bace2,Beta Secretase 2,Beta Site Amyloid Beta A4 Precursor Protein Cleaving Enzyme 2,Beta-secretase 2,Beta-site amyloid precursor pro
Application:
IHC
Concentration:
0.8 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human BACE2
Uniprot:
Q9Y5Z0
Synonyms:
56 kDa aspartic-like protease;AEPLC;ALP56;ASP1;ASP21;Aspartic-like protease 56 kDa;aspartyl protease 1;BAE2;beta-secretase 2;beta-site amyloid beta A4 precursor protein-cleaving enzyme 2;Beta-site amyloid precursor protein cleaving enzyme 2;beta-site APP-cleaving enzyme 2;CDA13;CEAP1;Down region aspartic protease;Down syndrome region aspartic protease;DRAP;memapsin-1;membrane-associated aspartic protease 1;SLCO3A1/BACE2 fusion;theta-secretase;transmembrane aspartic proteinase Asp1
Extra Details:
This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice