E-AB-53525
EFNB1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-53525
- Additional Names:
- CFND,CFNS,Craniofrontonasal syndrome (craniofrontonasal dysplasia),EFL 3,EFL-3,EFL3,EFNB1,ELK ligand,ELK-L,EPH-related receptor tyrosine kinase ligand 2,EPLG2,Elk L,Eph related receptor tyrosine kinase ligand 2,Ephrin-B1,LERK 2,LERK-2,LERK2,Ligand o
- Application:
- IHC
- Concentration:
- 0.9 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human EFNB1
- Uniprot:
- P98172
- Synonyms:
- CFND;CFNS;EFB1;EFL-3;EFL3;ELK ligand;Elk-L;eph-related receptor tyrosine kinase ligand 2;ephrin-B1;EPLG2;LERK2
- Extra Details:
- Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase.
- Shipping Conditions:
- Blue Ice