E-AB-53452
PLA2G16 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-53452
- Additional Names:
- AdPLA,Adipose specific PLA2,Adipose specific phospholipase A2,Adipose-specific phospholipase A2,Ca independent phospholipase A1/2,Group XVI phospholipase A1/A2,Group XVI phospholipase A2,H REV107 1,H rev 107 protein homolog,H-rev 107 protein homolog,HRAS
- Application:
- IHC
- Concentration:
- 1.1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human PLA2G16
- Uniprot:
- P53816
- Synonyms:
- adipose-specific phospholipase A2;adipose-specific PLA2;AdPLA;Ca-independent phospholipase A1/2;group XVI phospholipase A1/A2;group XVI phospholipase A2;H-rev 107 protein homolog;H-REV107;H-REV107-1;HRAS-like suppressor 1;HRAS-like suppressor 3;HRASLS3;HREV107;HREV107-1;HREV107-3;HRSL3;phospholipase A and acyltransferase 3;phospholipase A/acyltransferase-3;phospholipase A2 group XVI;PLA2G16;PLAAT-3;renal carcinoma antigen NY-REN-65
- Extra Details:
- Secretory phopholipase A2 (PLA2) enzymes cleave an acyl ester bond in the sn-2 position of glycerophospholipids. These extracellular proteins have a high disulfide bond content, low molecular mass (14 kDa), and require mM levels of Ca2+ for catalysis. They play a crucial role in the generation of arachidonates and eicosanoids, and have a number of biological actions including immunological responses, inflammation, cellular proliferation, vasoconstriction, and bronchioconstriction. Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue (By similarity). N- and O-acylation activity is hardly detectable. Might decrease protein phosphatase 2A (PP2A) activity.
- Shipping Conditions:
- Blue Ice