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E-AB-53438

GPC3 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-53438
Additional Names:
DGSX,GPC3,GTR2 2,GTR2-2,Glypican proteoglycan 3,Glypican-3 [Precursor],Gpc3,Heparan sulphate proteoglycan,Intestinal protein OCI 5,Intestinal protein OCI-5,MXR7,OCI 5,OCI-5,OCI5,SDYS,SGB,SGBS,SGBS1,Secreted glypican-3
Application:
IHC
Concentration:
1.8 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human GPC3
Uniprot:
P51654
Synonyms:
DGSX;glypican proteoglycan 3;glypican-3;GTR2-2;heparan sulphate proteoglycan;intestinal protein OCI-5;MXR7;OCI-5;SDYS;secreted glypican-3;SGB;SGBS;SGBS1
Extra Details:
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice