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E-AB-53424

ECT2 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-53424
Additional Names:
ECT 2,ECT2 protein,Epithelial cell transforming sequence 2,Epithelial cell transforming sequence 2 oncogene,Epithelial cell transforming sequence 2 oncogene protein,FLJ10461,MGC138291
Application:
IHC
Concentration:
1.02 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human ECT2
Uniprot:
Q9H8V3
Synonyms:
ARHGEF31;epithelial cell-transforming sequence 2 oncogene;protein ECT2
Extra Details:
The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators.The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases.In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver.Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.Several transcript variants encoding different isoforms have been found for this gene.
Shipping Conditions:
Blue Ice