E-AB-53394
MAFA Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-53394
- Additional Names:
- HMafA,MAFA,Mafa,Pancreatic beta cell specific transcriptional activator,Pancreatic beta-cell-specific transcriptional activator,RIPE3b1,Transcription factor MafA,Transcription factor RIPE3b1,v maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
- Application:
- WB
- Concentration:
- 1.2 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human MAFA
- Uniprot:
- Q8NHW3
- Synonyms:
- hMafA;INSDM;pancreatic beta-cell-specific transcriptional activator;RIPE3b1;RIPE3b1 factor;transcription factor MafA;transcription factor RIPE3b1;v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A;V-maf musculoaponeurotic fibrosarcoma oncogene homolog A
- Extra Details:
- Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. c-Maf (Maf-2) and the closely related family members.MAFA acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity.
- Shipping Conditions:
- Blue Ice