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E-AB-53391

DDC Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-53391
Additional Names:
AADC,Aromatic L Amino Acid Decarboxylase,Aromatic-L-amino-acid decarboxylase,DDC,DDC_HUMAN,DOPA decarboxylase,DOPA decarboxylase (aromatic L-amino acid decarboxylase)
Application:
WB
Concentration:
0.8 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human DDC
Uniprot:
P20711
Synonyms:
AADC;aromatic-L-amino-acid decarboxylase;DOPA decarboxylase;dopa decarboxylase (aromatic L-amino acid decarboxylase)
Extra Details:
The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Shipping Conditions:
Blue Ice