E-AB-53339
TBX1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-53339
- Additional Names:
- Brachyury,CAFS,CTHM,DGCR,DGS,DORV,T box,T box 1,T box 1 transcription factor,T box 1 transcription factor C,T box protein 1,T box transcription factor TBX 1,T box transcription factor TBX1,T-box protein 1,T-box transcription factor TBX1,TBX 1,TBX 1C,tbx1
- Application:
- IHC, WB
- Concentration:
- 0.7 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human TBX1
- Uniprot:
- O43435
- Synonyms:
- brachyury;CAFS;CATCH22;CTHM;DGCR;DGS;DORV;T-box 1 transcription factor C;T-box transcription factor TBX1;TBX1C;Testis-specific T-box protein;TGA;VCF;VCFS
- Extra Details:
- This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Shipping Conditions:
- Blue Ice