E-AB-53327
SASH1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-53327
- Additional Names:
- 2500002E12Rik,KIAA0790,PEPE 1,PEPE1,Proline glutamate repeat containing protein,Proline-glutamate repeat-containing protein,RP3 323M4.1,SAM and SH3 domain containing 1,SAM and SH3 domain containing protein 1,SAM and SH3 domain-containing,dJ323M4,dJ323M4.1
- Application:
- IHC, WB
- Concentration:
- 0.78 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human SASH1
- Uniprot:
- O94885
- Synonyms:
- CAPOK;dJ323M4.1;DUH1;proline-glutamate repeat-containing protein;SAM and SH3 domain-containing protein 1;SH3D6A
- Extra Details:
- This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients.
- Shipping Conditions:
- Blue Ice