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E-AB-53322

RAC2 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-53322
Additional Names:
EN 7,EN-7,EN7,GX,HSPC 022,HSPC022,RAC 2,RAC2,Rac2,Ras related C3 botulinum toxin substrate,Ras related C3 botulinum toxin substrate 2,Ras related C3 botulinum toxin substrate 2 (rho family,p21 Rac 2,p21 Rac2,p21-Rac2,p21Rac2,small GTP binding protein Rac2
Application:
IHC
Concentration:
1.02 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human RAC2
Uniprot:
P15153
Synonyms:
EN-7;Gx;HSPC022;IMD73A;IMD73B;IMD73C;p21-Rac2;ras-related C3 botulinum toxin substrate 2;ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2);Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2);small G protein
Extra Details:
RAC2,also named as GX,belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses,such as secretory processes,phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome.
Shipping Conditions:
Blue Ice