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E-AB-53284

MCAM Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-53284
Additional Names:
A32 antigen,CD 146,CD146,CD146 antigen,Cell surface glycoprotein MUC18,Cell surface glycoprotein P1H12,Gicerin,Mcam,Melanom,Melanoma adhesion molecule,Melanoma associated antigen A32,Melanoma associated antigen MUC18,Melanoma associated glycoprotein MUC18
Application:
IHC, WB
Concentration:
1.14 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human MCAM
Uniprot:
P43121
Synonyms:
CD146;cell surface glycoprotein MUC18;cell surface glycoprotein P1H12;Gicerin;HEMCAM;melanoma adhesion molecule;Melanoma cell adhesion molecule;melanoma-associated antigen A32;melanoma-associated antigen MUC18;MelCAM;METCAM;MUC18;S-endo 1 endothelial-associated antigen
Extra Details:
CD146,also known as melanoma cell adhesion molecule (MCAM) or MUC18,originally identified as a biomarker of melanoma progression,is a transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily . Structurally,it consists of five Ig domains,a transmembrane domain,and a cytoplasmic region. In normal adult tissue,CD146 is primarily expressed by vascular endothelium and smooth muscle. CD146 is a key cell adhesion protein in vascular endothelial cell activity and angiogenesis,and has been used as marker of circulating endothelium cells (CECs) .
Shipping Conditions:
Blue Ice