E-AB-53275
TCF7 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-53275
- Additional Names:
- FLJ36364,MGC47735,OTTHUMP00000159391,T cell factor 1,T cell specific transcription factor 1,T-cell factor 1,T-cell-specific transcription factor 1,TCF-1,TCF-7,TCF1,TCF7,TCF7 transcription factor 7,Tcf7,Tran,Transcription factor 7 (T cell specific HMG box)
- Application:
- IHC
- Concentration:
- 0.78 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human TCF7
- Uniprot:
- P36402
- Synonyms:
- T-cell-factor-7;T-cell-specific transcription factor 1;TCF-1;transcription factor 7;transcription factor 7 (T-cell specific, HMG-box)
- Extra Details:
- This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators.This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development.The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway.Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation.Alternative splicing results in multiple transcript variants.Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling.
- Shipping Conditions:
- Blue Ice