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E-AB-53270

PDK4 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-53270
Additional Names:
FLJ40832,PDK4,Pdk4,Pyruvate dehydrogenase [lipoamide] kinase isozyme 4 mitochondrial ,Pyruvate dehydrogenase kina,Pyruvate dehydrogenase kinase 4,Pyruvate dehydrogenase kinase isoenzyme 4,[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4,mitochondrial
Application:
WB
Concentration:
0.72 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human PDK4
Uniprot:
Q16654
Synonyms:
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial;[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial;Pyruvate dehydrogenase kinase isoform 4;pyruvate dehydrogenase kinase, isoenzyme 4;pyruvate dehydrogenase kinase, isozyme 4;pyruvate dehydrogenase, lipoamide, kinase isozyme 4, mitochondrial
Extra Details:
This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
Shipping Conditions:
Blue Ice