E-AB-53242
BECN1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-53242
- Additional Names:
- APG6,ATG 6,ATG6,ATG6 autophagy related 6 homolog,BECN 1,BECN1,Bcl-2-interacting protein beclin,Beclin 1 (coiled coil moesin like BCL2 interacting protein),Beclin 1 autophagy related,Beclin-1,Beclin1,Becn1,C,Coiled coil myosin like BCL2 interacting protein
- Application:
- IHC, WB
- Concentration:
- 0.84 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human BECN1
- Uniprot:
- Q14457
- Synonyms:
- ATG6;ATG6 autophagy related 6 homolog;beclin 1 (coiled-coil, moesin-like BCL2-interacting protein);beclin 1, autophagy related;beclin-1;beclin1;coiled-coil myosin-like BCL2-interacting protein;Protein GT197;testis secretory sperm-binding protein Li 215e;VPS30
- Extra Details:
- Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.
- Shipping Conditions:
- Blue Ice