E-AB-53167
RAPSN Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-53167
- Additional Names:
- 43 kD receptor associated protein of the synapse,43 kDa postsynaptic protein,43 kDa receptor-associated protein of the synapse,Acetylcholine receptor associated 43 kda protein ,Acetylcholine receptor-associated 43 kDa protein,CMS1D,CMS1E,MGC3597,RAP,RAPSN
- Application:
- IHC
- Concentration:
- 0.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human RAPSN
- Uniprot:
- Q13702
- Synonyms:
- 43 kda postsynaptic protein;43 kDa receptor-associated protein of the synapse;acetylcholine receptor-associated 43 kda protein;CMS11;CMS4C;FADS;FADS2;RAPSYN;RING finger protein 205;RNF205
- Extra Details:
- This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- Shipping Conditions:
- Blue Ice