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E-AB-53162

ASNA1 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-53162
Additional Names:
1,ARSA,ARSA 1,ARSA I,ARSA-I,ARSA1,ARSAI,ATP binding,ATP-binding,ArsA arsenite transporter,ArsA arsenite transporter ATP binding homolog 1,Arsenical pump driving ATPase,Arsenical pump-drivi,E. coli,homolog 1 (bacterial),homolog of
Application:
IHC
Concentration:
1.26 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human ASNA1
Uniprot:
O43681
Synonyms:
arsA arsenite transporter, ATP-binding, homolog 1;ARSA-I;ARSA1;Arsenical pump-driving ATPase;Arsenite-stimulated ATPase;ASNA-I;ASNA1;ATPase GET3;golgi to ER traffic 3 homolog;hARSA-I;hASNA-I;transmembrane domain recognition complex 40 kDa ATPase subunit;TRC40
Extra Details:
ASNA1 (also known as TRC40) is a highly conserved ATPase involved in efflux of arsenite and antimonite. Reduced ASNA1 expression is associated with significant inhibition of cell growth,increased apoptosis and increased sensitivity to cisplatin and arsenite.Thus ASNA1 is proposed to be a target to overcome resistance to cancer chemotherapy. In addition,ASNA1 has been identified as an ER targeting factor for tail-anchored proteins in the posttranslational membrane insertion pathway.
Shipping Conditions:
Blue Ice