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E-AB-53147

TSTA3 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-53147
Additional Names:
3 5 epimerase/4 reductase,5-epimerase-4-reductase,EC 1.1.1.271,FCL,FX,GDP 4 keto 6 deoxy D mannose 3 5 epimerase 4 reductase,GDP 4 keto 6 deoxy D mannose epimerase reductase,GDP L fucose synthase,GDP-4-keto-6-deoxy-D-mannose-3,GDP-L-fucose synt,anti TSTA3
Application:
IHC
Concentration:
1.44 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human TSTA3
Uniprot:
Q13630
Synonyms:
3-5 epimerase/4-reductase;FX;GDP-4-keto-6-deoxy-D-mannose epimerase-reductase;GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase;GDP-L-fucose synthase;P35B;Protein FX;red cell NADP(H)-binding protein;SDR4E1;short chain dehydrogenase/reductase family 4E, member 1;Short-chain dehydrogenase/reductase family 4E member 1;testis tissue sperm-binding protein Li 45a;tissue specific transplantation antigen 3;tissue specific transplantation antigen P35B;TSTA3
Extra Details:
Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.
Shipping Conditions:
Blue Ice