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E-AB-53131

THG1L Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-53131
Additional Names:
ICF45,Interphase cytoplasmic foci protein 45,Probable tRNA(His) guanylyltransferase,THG1,THG1L,tRNA histidine guanylyltransferase 1 like (S. cerevisiae),tRNA-histidine guanylyltransferase
Application:
IHC
Concentration:
0.9 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human THG1L
Uniprot:
Q9NWX6
Synonyms:
hTHG1;ICF45;IHG-1;IHG1;induced by high glucose-1;induced in high glucose-1;interphase cytoplasmic foci protein 45;probable tRNA(His) guanylyltransferase;SCAR28;THG1;tRNA-histidine guanylyltransferase
Extra Details:
The protein encoded by this gene is a mitochondrial protein that is induced by high levels of glucose and is associated with diabetic nephropathy. The encoded protein appears to increase mitochondrial biogenesis, which could lead to renal fibrosis. Another function of this protein is that of a guanyltransferase, adding GMP to the 5' end of tRNA(His). Several transcript variants encoding different isoforms have been found for this gene.
Shipping Conditions:
Blue Ice