E-AB-53112
CNOT7 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-53112
- Additional Names:
- BTG1 binding factor 1,BTG1-binding factor 1,CAF 1,CAF-1,CAF1,CCR4 NOT transcription complex subunit 7,CCR4 associated factor 1,CCR4-NOT transcription complex subunit ,CCR4-associated factor 1,Carbon catabolite repressor protein (CCR4) associative factor 1
- Application:
- IHC
- Concentration:
- 0.96 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human CNOT7
- Uniprot:
- Q9UIV1
- Synonyms:
- BTG1-binding factor 1;CAF-1;CAF1;Caf1a;carbon catabolite repressor protein (CCR4)-associative factor 1;CCR4-associated factor 1;CCR4-NOT transcription complex subunit 7;hCAF-1
- Extra Details:
- The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.CNOT7 (CCR4-NOT Transcription Complex Subunit 7) is a Protein Coding gene. Among its related pathways are Deadenylation-dependent mRNA decay and Gene Expression. GO annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is CNOT8.
- Shipping Conditions:
- Blue Ice