E-AB-53015
PCBD1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-53015
- Additional Names:
- 4 alpha hydroxy tetrahydropterin dehydratase,4-alpha-hydroxy-tetrahydropterin dehydratase,6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of ,6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)
- Application:
- IHC, WB
- Concentration:
- 1.62 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human PCBD1
- Uniprot:
- P61457
- Synonyms:
- 4-alpha-hydroxy-tetrahydropterin dehydratase;6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1);DCOH;Dimerization cofactor of hepatocyte nuclear factor 1-alpha;dimerizing cofactor for HNF1;PCBD;PCD;phenylalanine hydroxylase-stimulating protein;PHS;Pterin carbinolamine dehydratase;pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha;pterin-4-alpha-carbinolamine dehydratase
- Extra Details:
- This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.
- Shipping Conditions:
- Blue Ice