E-AB-52978
ARIH2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-52978
- Additional Names:
- ARI2,ARIH 2,Ari 2,Ari-2,Ariadne 2,Ariadne 2 protein homolog,Ariadne RBR E3 ubiquitin protein ligase 2,Arih2,E3 ubiq,E3 ubiquitin protein ligase ARIH2,HT005,all trans retinoic acid inducible RING finger,ariadne homolog 2,ariadne homolog 2 (Drosophila)
- Application:
- IHC
- Concentration:
- 1.2 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human ARIH2
- Uniprot:
- O95376
- Synonyms:
- all-trans retinoic acid inducible RING finger;ARI2;ariadne homolog 2;E3 ubiquitin-protein ligase ARIH2;protein ariadne-2 homolog;RING-type E3 ubiquitin transferase ARIH2;TRIAD1;Triad1 protein
- Extra Details:
- TRIAD1, also known as ARIH2 (ariadne homolog 2) or ARI2, is a 493 amino acid protein that contains one IBR-type zinc finger and two RING-type zinc fingers and belongs to the ariadne subfamily of RBR proteins. Localized to the nucleus, TRIAD1 interacts with UBE2L3 and is thought to act as an E3 ubiquitin-protein ligase, functioning to accept ubiquitin from E2 ubiquitin-conjugating enzymes and transfer the acquired ubiquitin residue to target substrates. TRIAD1 is subject to post-translational DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding TRIAD1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.
- Shipping Conditions:
- Blue Ice