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E-AB-52884

PPP1R3C Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-52884
Additional Names:
regulatory (inhibitor) subunit 3C, regulatory inhibitor subunit 5,OTTHUMP00000020089,PP1 subunit R5,PPP1R5 ,PPR3C,Phosphatase 1,Protein phosphatase 1 regulatory subunit 3C,Protein phosphatase 1 regulatory subunit 5,Protein t,ppp1r3c,protein phosphatase 1
Application:
IHC
Concentration:
0.9 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human PPP1R3C
Uniprot:
Q9UQK1
Synonyms:
Phosphatase 1, regulatory inhibitor subunit 5;PP1 subunit R5;PPP1R5;protein phosphatase 1 regulatory subunit 3C;protein phosphatase 1 regulatory subunit 5;protein phosphatase 1, regulatory (inhibitor) subunit 3C;protein targeting to glycogen;PTG
Extra Details:
This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease.
Shipping Conditions:
Blue Ice