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E-AB-52842

PPM1B Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-52842
Additional Names:
MGC21657,OTTHUMP00000158953,OTTHUMP00000158954,OTTHUMP00000158955,OTTHUMP00000202394,OTTHUMP00000202395,OTTHUMP00000202399,PP2C beta,PP2C beta X,PP2C-beta,PP2CB,PP2Cbeta,PPC2BETAX,PPM 1B,PPM1B,Ppm1b,Protein phosphatase 1B (formerly 2C) magnesium dependent
Application:
IHC
Concentration:
1.44 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human PPM1B
Uniprot:
O75688
Synonyms:
PP2C-beta;PP2C-beta-X;PP2CB;PP2CBETA;PPC2BETAX;protein phosphatase 1B;Protein phosphatase 2C isoform beta;protein phosphatase 2C-like protein
Extra Details:
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.
Shipping Conditions:
Blue Ice