E-AB-52751
TLE6 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-52751
- Additional Names:
- GRG6,PREMBL,Transducin Like Enhancer Of Split 6
- Application:
- IHC
- Concentration:
- 1.38 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human TLE6
- Uniprot:
- Q9H808
- Synonyms:
- GRG6;PREMBL;transducin like enhancer of split 6;transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila);transducin-like enhancer protein 6
- Extra Details:
- This gene encodes a member of the Groucho/ transducin-like Enhancer of split family of transcriptional co-repressors. The encoded protein is a component of the mammalian subcortical maternal complex, which is required for preimplantation development. In mouse, knock out of this gene results in cleavage-stage embryonic arrest resulting from defective cytoplasmic F-actin meshwork formation and asymmetric cell division. In human, an allelic variant in this gene is associated with preimplantation embryonic lethality. Alternative splicing results in multiple transcript variants.
- Shipping Conditions:
- Blue Ice