E-AB-52701
ZC3H7A Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-52701
- Additional Names:
- HSPC055 ,ZC3H7 ,ZC3HDC7 ,Zinc finger CCCH domain containing protein 7A,zinc finger CCCH type containing 7,zinc finger CCCH type containing 7A,zinc finger CCCH type domain containing 7,zinc finger protein AY163807
- Application:
- IHC
- Concentration:
- 0.9 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human ZC3H7A
- Uniprot:
- Q8IWR0
- Synonyms:
- HSPC055;ZC3H7;ZC3HDC7;zinc finger CCCH domain-containing protein 7A;zinc finger CCCH-type domain containing 7;zinc-finger protein AY163807
- Extra Details:
- The zinc finger CCCH domain-containing protein 7A (ZC3H7A), also known as ZC3H7, HSPC055 or ZC3HDC7, is a 971 amino acid protein that contains a C3H1-type zinc finger domain, three C3H1-type zinc fingers and three TPR repeats. Belonging to the ZC3H12 family, ZC3H7A localizes to the nucleus. Existing as two alternatively spliced isoforms, ZC3H7A is encoded by a gene located on human chromosome 16p13.13. Chromosome 16 makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.
- Shipping Conditions:
- Blue Ice