E-AB-52670
TIMM8A Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-52670
- Additional Names:
- DDP,DDP 1,DDP1,DFN 1,DFN1,Deafness dystonia protein 1,Deafness/dystonia peptide,MGC12262,MTS,Mitochondrial import inner membrane translocase subunit Tim8 A,TIM 8A,TIM8,TIM8A,TIMM 8A,Translocase of inner mitochondrial membrane 8 homolog A,X li,timm8a
- Application:
- IHC
- Concentration:
- 1.62 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human TIMM8A
- Uniprot:
- O60220
- Synonyms:
- DDP;DDP1;deafness dystonia protein 1;deafness/dystonia peptide;DFN1;mitochondrial import inner membrane translocase subunit Tim8 A;MTS;TIM8;translocase of inner mitochondrial membrane 8 homolog A;X-linked deafness dystonia protein
- Extra Details:
- This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome, an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Shipping Conditions:
- Blue Ice