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E-AB-52666

PFKM Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-52666
Additional Names:
6 Phosphofructokinase Muscle Type,6-phosphofructokinase,6-phosphofructokinase muscle type,EC 2.7.1.1,EC 2.7.1.11,GSD7,K6PF,MGC8699,PFK,PFK-A,PFKA,PFKL,PFKM,PFKP,PFKX,Phosphofructo 1 Kinase Isozyme A,Phosphofructo-1-kinase isozyme A,muscle type
Application:
IHC
Concentration:
0.9 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human PFKM
Uniprot:
P08237
Synonyms:
6-phosphofructo-1-kinase;6-phosphofructokinase type A;6-phosphofructokinase, muscle type;ATP-dependent 6-phosphofructokinase, muscle type;ATP-PFK;GSD7;PFK-1;PFK-A;PFK1;PFKA;PFKX;phosphofructo-1-kinase isozyme A;phosphofructokinase 1;phosphofructokinase-M;phosphofructokinase, polypeptide X;phosphohexokinase;PPP1R122;protein phosphatase 1, regulatory subunit 122
Extra Details:
Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
Shipping Conditions:
Blue Ice