TUBGCP4 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:: E-AB-52657
Additional Names:: 76P,FLJ14797,GCP 4,GCP4,Gamma tubulin complex component 4,Gamma tubulin ring complex protein,Gamma tubulin ring complex protein (76p gene),Gamma-ring complex protein 76 kDa,Grip76,Hgrip76,TUBGCP 4,TUBGCP4,Tubulin gamma complex associated protei,h76p,hGCP4
Application:: WB
Concentration:: 0.66 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Fusion protein of human TUBGCP4
Uniprot:: Q9UGJ1
Synonyms:: 76P;gamma tubulin ring complex protein (76p gene);gamma-ring complex protein 76 kDa;gamma-tubulin complex component 4;GCP-4;GCP4;Grip76;MCCRP3
Extra Details:: This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.TUBGCP4 (Tubulin Gamma Complex Associated Protein 4) is a Protein Coding gene. Diseases associated with TUBGCP4 include Microcephaly And Chorioretinopathy, Autosomal Recessive, 3 and Autosomal Recessive Chorioretinopathy-Microcephaly Syndrome. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Cell Cycle, Mitotic. GO annotations related to this gene include structural constituent of cytoskeleton. An important paralog of this gene is TUBGCP6.

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