E-AB-52586
ITM2B Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-52586
- Additional Names:
- ABRI,ABri/ADan amyloid peptide,BRI,BRI 2,BRI2,BRICD 2B,BRICD2B,BRICHOS domain containing 2B,E25B,E3 16,E3-16,FBD,ITM 2B,ITM2B,Immature BRI2,Integral membrane protein 2B,Protein E25B,RDGCA,Transmembrane protein BRI,imBRI2
- Application:
- WB
- Concentration:
- 0.96 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human ITM2B
- Uniprot:
- Q9Y287
- Synonyms:
- ABRI;ABri/ADan amyloid peptide;BRI;BRI2;BRICD2B;BRICHOS domain containing 2B;E25B;E3-16;epididymis secretory sperm binding protein;FBD;imBRI2;immature BRI2;integral membrane protein 2B;Protein E25B;RDGCA;transmembrane protein BRI
- Extra Details:
- Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.
- Shipping Conditions:
- Blue Ice