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E-AB-52526

CD86 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-52526
Additional Names:
Activation B7-2 antigen,Activation B7-2 antigen 3,B-lymphocyte activation antigen B7-2,B-lymphocyte activation antigen B7-2 2,B7,B7 2,B7-2,B7.2,B70,B72 antigen,BU63,CD28 antigen ligand 2,CD28 antigen ligand 2 2,CD28LG2,CD86,CD86 antige,CD86 antigen,Cd28l2
Application:
IHC
Concentration:
0.6 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human CD86
Uniprot:
P42081
Synonyms:
Activation B7-2 antigen;B-lymphocyte activation antigen B7-2;B7-2;B7.2;B70;BU63;CD28LG2;CD86 antigen (CD28 antigen ligand 2, B7-2 antigen);CTLA-4 counter-receptor B7.2;FUN-1;LAB72;T-lymphocyte activation antigen CD86
Extra Details:
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Shipping Conditions:
Blue Ice