E-AB-52436
UBA7 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-52436
- Additional Names:
- D8,MGC12713,UBA1,UBA1B,UBA7,UBE 2,UBE1L,UBE2,Ube 1L,Ubiquitin Activating Enzyme E1 Like,Ubiquitin activa,Ubiquitin activating enzyme 2,Ubiquitin activating enzyme E1 homolog,ubiquitin activating enzyme E1,ubiquitin activating enzyme E1 homolog B
- Application:
- IHC
- Concentration:
- 0.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human UBA7
- Uniprot:
- P41226
- Synonyms:
- D8;UBA1, ubiquitin-activating enzyme E1 homolog B;UBA1B;UBA7, ubiquitin-activating enzyme E1;UBE1L;UBE2;ubiquitin-activating enzyme 7;ubiquitin-activating enzyme E1 homolog;ubiquitin-activating enzyme E1-related protein;ubiquitin-activating enzyme-2;ubiquitin-like modifier-activating enzyme 7
- Extra Details:
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.
- Shipping Conditions:
- Blue Ice