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E-AB-52423

VRK3 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-52423
Additional Names:
Inactive serine/threonine-protein kinase VRK3,Serine/threonine-protein pseudokinase VRK3,VRK3,Vaccinia-related kinase 3
Application:
IHC
Concentration:
0.6 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human VRK3
Uniprot:
Q8IV63
Synonyms:
inactive serine/threonine-protein kinase VRK3;serine/threonine-protein kinase VRK3;serine/threonine-protein pseudokinase VRK3;vaccinia related kinase 3;Vaccinia-related kinase 3
Extra Details:
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases.In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis.In vitro assays indicate the protein lacks phosphorylation activity.The protein, however, likely retains its substrate binding capability.This gene is widely expressed in human tissues and its protein localizes to the nucleus.Alternative splicing results in multiple transcripts encoding different isoforms.
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Blue Ice