E-AB-52385
ZNF354A Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-52385
- Additional Names:
- and developmentally regulated protein 1, ischemia,EZNF,HKL1,HLK1,Homo sapiens zinc finger protein 354A,KID 1,KID1,Kidney,Renal transcription factor Kid 1 ,TCF-17,TCF17,Transcription factor 17,Z354A,ZNF354,Zinc finger protein 354A,Zinc finger protein eZNF
- Application:
- IHC
- Concentration:
- 0.5 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human ZNF354A
- Uniprot:
- O60765
- Synonyms:
- epididymis luminal protein 104;EZNF;HEL104;HKL1;KID-1;KID1;TCF17;transcription factor 17;zinc finger protein 354A;zinc finger protein eZNF
- Extra Details:
- ZNF354A, also called EZNF, KID-1 or TCF17, belongs to the Krueppel C2H2-type zinc-finger family of proteins that contain KRAB domains and act as transcriptional regulators. Expressed primarily in the adult kidney, ZNF354A is a transcriptional repressor that plays a role in late renal development and is suppressed after renal ischemia. The N-terminus of ZNF354A contains the KRAB domain which confers transcriptional repressor activity, while the C-terminus contains multiple Cys2His2-zinc fingers. ZNF354A is located in the nucleolus and is thought to specifically influence development of the proximal tubule by shutting off dispensable or inhibitory genes. Reduced ZNF354A expression prevents proper cell differentiation and may, therefore, be implicated in renal carcinoma.
- Shipping Conditions:
- Blue Ice