E-AB-52260
FNDC3B Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-52260
- Additional Names:
- DKFZp686D14170 ,DKFZp762K137,FAD104,FLJ23399,Factor for adipocyte differentiation 104,HCV NS5A binding protein 37 ,MGC10002,NS5ABP37,PRO4979,YVTM2421,fibronectin type III domain containing 3B
- Application:
- IHC
- Concentration:
- 1.8 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Full length fusion protein
- Uniprot:
- Q53EP0
- Synonyms:
- factor for adipocyte differentiation 104;FAD104;fibronectin type III domain-containing protein 3B;HCV NS5A-binding protein 37;PRO4979;YVTM2421
- Extra Details:
- Adipogenesis, the process of transforming pre-adipocytes into mature fat cells, is of particular interest due to the role adipocytes play in obesity and type II diabetes. Adipocytes have been shown to affect a variety of functions, including hemostasis, angiogenesis and energy balance, by secreting hormones and bioactive peptides. The FNDC3B protein, also designated FAD104 (factor for adipocyte differentiation 104) or HCV NS5A-binding protein 37, is expressed during early adipogenesis. Belonging to the FNDC3 family of proteins, FNDC3B is a 1,204 amino acid protein that contains nine fibronectin type-III domains. FNDC3B-deficient mice die within one day of birth, suggesting that FNDC3B is crucial for postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B function displayed a reduction in stress fiber formation, indicating a role for FNDC3B in cell proliferation, adhesion, spreading and migration.
- Shipping Conditions:
- Blue Ice