E-AB-52225
TRIM23 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-52225
- Additional Names:
- ADP ribosylation factor domain protein 1,ADP-ribosylation factor domain-containing protein 1,ARF domain protein 1,ARFD1,E3 ubiquitin-protein ligase TRIM23,GTP binding protein ARD 1,GTP-binding protein ARD-1,N-acet,N-acetyltransferase ARD1 human homolog of
- Application:
- IHC
- Concentration:
- 0.9 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human TRIM23
- Uniprot:
- P36406
- Synonyms:
- ADP-ribosylation factor domain protein 1, 64kDa;ADP-ribosylation factor domain-containing protein 1;ARD1;ARF domain protein 1;ARFD1;E3 ubiquitin-protein ligase TRIM23;GTP-binding protein ARD-1;RING finger protein 46;RING-type E3 ubiquitin transferase TRIM23;RNF46;tripartite motif protein TRIM23;tripartite motif-containing protein 23
- Extra Details:
- The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.
- Shipping Conditions:
- Blue Ice