E-AB-52223
TIA1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-52223
- Additional Names:
- Cytotoxic granule associated RNA binding protein,Cytotoxic granule associated RNA binding protein 1,Nucleolysin TIA 1 isoform p40 ,Nucleolysin TIA-1 isoform p40,Nucleolysin TIA1 isoform p40,RNA b,mTIA-1,p40 TIA 1,p40-TIA-1,p40-TIA-1 (containing p15-TIA-1)
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Full length fusion protein
- Uniprot:
- P31483
- Synonyms:
- ALS26;nucleolysin TIA-1;nucleolysin TIA-1 isoform p40;p40-TIA-1;p40-TIA-1 (containing p15-TIA-1);RNA-binding protein TIA-1;T-cell-restricted intracellular antigen-1;TIA-1;WDM
- Extra Details:
- The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
- Shipping Conditions:
- Blue Ice