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E-AB-52167

RCHY1 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-52167
Additional Names:
ARNIP,Androgen receptor N terminal interacting protein,Androgen receptor N-terminal-interacting protein,CH-rich-interacting match with PLAG1,CHIMP,E3 ubiquitin-protein ligase Pirh2,hARNIP,hPirh2,p53 induced protein with a RING H2 domain,p53-induced RING-H
Application:
IHC, WB
Concentration:
0.84 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human RCHY1
Uniprot:
Q96PM5
Synonyms:
Androgen receptor N-terminal-interacting protein;androgen-receptor N-terminal-interacting protein;ARNIP;CH-rich interacting match with PLAG1;CH-rich-interacting match with PLAG1;CHIMP;E3 ubiquitin-protein ligase Pirh2;p53-induced protein with a RING-H2 domain;p53-induced RING-H2 protein;PIRH2;PRO1996;ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase;RING finger and CHY zinc finger domain-containing protein 1;RING finger protein 199;RING-type E3 ubiquitin transferase RCHY1;RNF199;ZCHY;zinc finger protein 363;zinc finger, CHY-type;ZNF363
Extra Details:
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Shipping Conditions:
Blue Ice