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E-AB-52164

PADI4 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-52164
Additional Names:
EC 3.5.3.15,HL 60 PAD,HL-60 PAD,PAD,PAD 4,PADI 4,PADI 5,PADI H protein,PADI4,PADI5,PDI 4,PDI 5,PDI4,PDI5,Padi4,Peptidyl arginine deiminase type IV,Peptidyl arginine deiminase type V,Peptidylarginine deiminase IV,Protein arginine,Protein arginine deiminase
Application:
IHC, WB
Concentration:
0.6 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human PADI4
Uniprot:
Q9UM07
Synonyms:
HL-60 PAD;PAD;PAD4;PADI-H protein;PADI5;PDI4;PDI5;peptidyl arginine deiminase, type IV;peptidyl arginine deiminase, type V;Peptidylarginine deiminase IV;protein-arginine deiminase type IV;protein-arginine deiminase type-4
Extra Details:
This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. PADI4 plays a role in the epigenetics, the deimination of arginines on histones 3 and 4 can act antagonistically to arginine methylation. The protein may be found in oligomers and binds 5 calcium ions per subunit. It catalyses the reaction: Protein L-arginine + H2O = protein L-citrulline + NH3.
Shipping Conditions:
Blue Ice