E-AB-52144
COX7A2L Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-52144
- Additional Names:
- mitochondrial,COX7A2L,COX7AR,COX7R,COX7RP,COX7a related protein,COX7a-related protein,Cytochrome c oxidase subunit 7A-related protein,Cytochrome c oxidase subunit 7A2 like,cytochrome c oxidase subunit 7A-related protein,cytochrome c oxidase subunit VII-r
- Application:
- IHC
- Concentration:
- 2.5 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Full length fusion protein
- Uniprot:
- O14548
- Synonyms:
- COX7a-related protein;COX7AR;COX7RP;cytochrome c oxidase subunit 7A-related protein, mitochondrial;cytochrome c oxidase subunit VII-related protein;cytochrome c oxidase subunit VIIa polypeptide 2 like;cytochrome c oxidase subunit VIIa-related protein;EB1;estrogen receptor binding CpG island;SCAF1;SCAFI;SIG81
- Extra Details:
- Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene.
- Shipping Conditions:
- Blue Ice